2025-09-09
Living with plaque psoriasis can be challenging, not only due to its visible skin manifestations but also because of the discomfort and lifestyle restrictions it brings. Patients and healthcare professionals are constantly seeking therapies that provide effective relief with manageable side effects. Plaque Psoriasis Apremilast has emerged as one of the innovative oral treatment options designed to improve the quality of life for individuals struggling with this chronic inflammatory disease.
As a pharmaceutical product offered by Jiangsu Run'an Pharmaceutical Co. Ltd., Apremilast is known for its unique mechanism of action and its convenient oral administration compared with traditional biologic injections. This article will explore the product's parameters, effectiveness, importance, and commonly asked questions to give readers a comprehensive understanding.
Apremilast is an oral phosphodiesterase 4 (PDE4) inhibitor that helps regulate the inflammatory response in patients with plaque psoriasis. Unlike biologics that target specific cytokines directly, Apremilast works by modulating the intracellular pathways that control the production of pro-inflammatory and anti-inflammatory mediators.
Key Highlights:
Oral small molecule therapy.
Non-biologic, avoiding the need for injections.
Demonstrated clinical efficacy in moderate to severe plaque psoriasis.
Manufactured and supplied by Jiangsu Run'an Pharmaceutical Co. Ltd., ensuring high-quality standards.
| Parameter | Description |
|---|---|
| Product Category | PDE4 Inhibitor, Oral Tablet |
| Primary Use | Treatment of moderate to severe plaque psoriasis |
| Manufacturer | Jiangsu Run'an Pharmaceutical Co. Ltd. |
| Dosage Strength | 30 mg per tablet |
| Recommended Dosage | 30 mg twice daily |
| Administration Route | Oral, with or without food |
| Common Adverse Effects | Diarrhea, nausea, headache, weight loss |
| Monitoring Requirements | Body weight, mood changes, renal function |
| Advantages | Oral formulation, non-biologic, convenient and effective in long-term use |
Psoriasis is not merely a cosmetic condition—it is a chronic inflammatory disease that can significantly impair daily activities and self-esteem. Traditional treatments often include topical therapies, phototherapy, or biologic injections. However, these may not be suitable for everyone.
Plaque Psoriasis Apremilast plays a crucial role because:
Convenience – Oral tablets provide ease of administration, improving patient compliance.
Safety Profile – Does not require routine laboratory monitoring like biologics.
Broad Suitability – Can be prescribed for patients who may not tolerate or have contraindications to injectable therapies.
Proven Efficacy – Clinical trials have demonstrated significant improvement in Psoriasis Area and Severity Index (PASI) scores.
When patients start therapy with Plaque Psoriasis Apremilast, they often report improvements in scaling, redness, and overall skin comfort. Importantly, the reduction in itch and visible lesions contributes to psychological well-being, which is often overlooked in treatment strategies.
Additionally, since Apremilast is an oral option, it offers independence and discretion, particularly valuable for those who prefer not to undergo injectable therapies or frequent hospital visits.
Q1: How does Plaque Psoriasis Apremilast work in the body?
A1: Apremilast inhibits the enzyme PDE4, which increases intracellular cyclic adenosine monophosphate (cAMP). This results in downregulation of pro-inflammatory cytokines (such as TNF-α, IL-17, and IL-23) and upregulation of anti-inflammatory mediators, thereby reducing skin inflammation and plaque formation.
Q2: How long does it take to see improvements after starting treatment?
A2: Clinical studies show that many patients notice improvement within 16 weeks of consistent treatment. However, response time can vary depending on the severity of the disease and patient-specific factors.
Q3: Can Plaque Psoriasis Apremilast be combined with other therapies?
A3: Yes, in certain cases it can be used alongside topical treatments or phototherapy. However, healthcare professionals should carefully assess each patient's condition to avoid unnecessary side effects.
Q4: Is Apremilast safe for long-term use?
A4: Long-term studies indicate that Apremilast maintains efficacy and safety over extended treatment periods. Continuous monitoring of weight and mood is recommended, but no routine blood monitoring is typically required.
The choice of manufacturer is as critical as the therapy itself. Jiangsu Run'an Pharmaceutical Co. Ltd. adheres to international quality standards to ensure safety, consistency, and reliability. With decades of expertise in pharmaceutical innovation, the company is dedicated to supporting healthcare professionals and improving patient lives.
Key Advantages of Choosing Our Product:
GMP-certified manufacturing facilities.
Global distribution capabilities.
Emphasis on patient-centered solutions.
Commitment to ongoing research and innovation.
For patients living with moderate to severe psoriasis, finding a reliable treatment that balances effectiveness, safety, and convenience is essential. Plaque Psoriasis Apremilast, manufactured by Jiangsu Run'an Pharmaceutical Co. Ltd., stands as a promising solution that empowers both patients and healthcare providers. Its oral administration, established efficacy, and favorable safety profile make it a practical alternative to conventional biologic therapies.
If you are a healthcare professional seeking more details or a patient interested in learning about treatment options, feel free to reach out for comprehensive product information and professional support. Contact us.